Obesity may boost risk of aggressive breast cancer in women
U.S. researchers are reporting that being obese may increase the risk of triple-negative breast cancer, an aggressive form of the disease.
They found that women who were overweight had a 35 percent higher risk of developing triple-negative breast cancer.
To investigate, researchers analyzed data from more than 155,000 women enrolled in a large study of the effects of hormone replacement therapy on menopausal women.
The team studied body mass index and physical activity among the women in the study who had triple negative breast cancer and the women who had estrogen receptor-positive breast cancers.
Researchers found that women with the highest BMI in the study had a 35 percent higher risk of triple-negative breast cancers, and a 39 percent higher risk of estrogen-fed breast cancers.
Triple-negative breast cancer tumours lack estrogen receptors needed for some breast cancer drugs to work. Approximately 10-20 percent of breast cancers are found to be triple-negative. For more information on triple-negative breast cancer, click here
According to the Canadian Breast Cancer Foundation
, breast cancer continues to be the leading type of cancer among Canadian women. One in nine Canadian women are expected to develop breast cancer during her lifetime.
The study was published in the journal Cancer Epidemiology, Biomarkers & Prevention
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